AFP011004

General Information

Protein Name Ice-structuring protein SS-8
UniProt ID P04368
Species Myoxocephalus scorpius (Shorthorn sculpin) (Cottus scorpius)
Sequence Length 45
Sequence
Structure AFDB ID: AF-P04368-F1-model_v4
Solvent Accessible Surface Area Total SASA 2856.64 Ų Polar SASA 1076.72 Ų Apolar SASA 3933.36 Ų

AFP011004000

Mutation Wild Type
Sequence
Thermal Hysteresis
PMID 4029130
DOI 10.1111/j.1432-1033.1985.tb09081.x
Protein Name shorthorn sculpin AFP SS-8
Thermal Hysteresis Tab.2 Properties of sculpin and flounder AFP, and the cleavage peptides of sculpin AFP.
Brief description
PMID: 4029130
DOI: 10.1111/j.1432-1033.1985.tb09081.x
1. High α-helical content (73%) in SS-8 correlates with strong antifreeze activity, while structural disruption abolishes activity.
2. Blocked N-terminal methionine in SS-8 is crucial for activity, as its removal reduces antifreeze activity despite minimal helical content change.

AFP011004001

Mutation 1del
Sequence
Thermal Hysteresis
PMID 4029130
DOI 10.1111/j.1432-1033.1985.tb09081.x
Protein Name shorthorn sculpin AFP CNBr SS-8
Thermal Hysteresis Tab.2 Properties of sculpin and flounder AFP, and the cleavage peptides of sculpin AFP.
Brief description
PMID: 4029130
DOI: 10.1111/j.1432-1033.1985.tb09081.x
1. High α-helical content (73%) in SS-8 correlates with strong antifreeze activity, while structural disruption abolishes activity.
2. Blocked N-terminal methionine in SS-8 is crucial for activity, as its removal reduces antifreeze activity despite minimal helical content change.